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May 14, 2011
Heavy beer drinking is linked to many negative consequences, though many beer drinkers tend to deny this fact (you can check out the discussion here). However, more and more of new scientific researches are pointing to numerous dangers and risks linked to increased beer consumption. Many heavy beer drinkers are in need of withdrawal help and assistance of specialists in order to prevent real danger to their health. In particular, according to the findings of a new study conducted by a group of Spanish specialists working for the Cancer Epidemiology Research Program at the Catalan Institute of Oncology in Barcelona, increased beer consumption is connected with higher risks of gastric cancer development.
Actually, this study was intended to complement another extended research from the European Prospective Investigation into Cancer and Nutrition program. More than 521,000 people of age from 35 to 70 took part in that study, and they were asked to consume various doses of alcoholic drinks on an everyday basis. It was found out that the prolonged consumption (up to 8-10 years) of 60 g of pure ethanol/alcohol from various alcoholic drinks is linked to 65% increased risks of gastric cancer.
According to Eric J. Duell, Ph.D., one of the leaders of Barcelona study, it was found that consuming about 30 mg of ethanol/alcohol directly from beer (that is equates to three 12-ounce cans of beer) every day increases the risks of gastric cancer by 75%. At that, no similar results or similar risks were detected for consumption of other alcoholic drinks like liquor or wine.
In addition, the study revealed that the risks of gastric cancer in beer lovers have certain genetic context. Those beer drinkers who have two copies of rs1230025 genes have way more increased risks of gastric cancer. Two more genes in our DNA, namely rs1230025 and rs283411, are also reported to increase the chances to develop gastric cancer. The mentioned genes influence the processes connected with alcohol metabolism in our body, but certain mutations of these genes can elevate gastric cancer risks even in those who are not much of beer drinkers.
“This is a classic gene-environment interaction,” said Duell. “Having both of these risks – heavy beer consumption and rs1230025 – appears to be worse in terms of gastric cancer risk than having just one or neither.” Gastric cancer in considered the second leading cause of death in the world, but its prevalence in lower in most of developed countries. The findings and analysis of the study have been presented at the 102th annual meeting of the American Association for Cancer Research.

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